Structure of PDB 5epl Chain A

Receptor sequence
>5eplA (length=54) Species: 9606 (Homo sapiens) [Search protein sequence]
GSEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLI
AFQN
3D structure
PDB5epl A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1.
ChainA
Resolution1.81 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A H9 V10 F11 A12 V13 W32 W35 E43 N47 L49 D50 R52 L53 H4 V5 F6 A7 V8 W27 W30 E38 N42 L44 D45 R47 L48
BS02 peptide A L49 P51 L44 P46
Gene Ontology
Biological Process
GO:0045892 negative regulation of DNA-templated transcription

View graph for
Biological Process
External links
PDB RCSB:5epl, PDBe:5epl, PDBj:5epl
PDBsum5epl
PubMed26807715
UniProtO00257|CBX4_HUMAN E3 SUMO-protein ligase CBX4 (Gene Name=CBX4)

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