Structure of PDB 5eom Chain A

Receptor sequence
>5eomA (length=349) Species: 9606 (Homo sapiens) [Search protein sequence]
DIAAQAKLVYHLNKYYNEKCQARKAAIAKTIREVCKVVSDVLKEVEVQEP
RFISSLNEMNRYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLK
LSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKM
VADTSEVKLRIRDRYVVQITPAFKCTGIWPRSAAHWPLPHIPWPGPNRVA
EVKAEGFNLLSKECHESDAWVLQFAEAENRLQMGGCRKKCLSILKTLRDR
HLELPGQPLNNYHMKTLVSYECEKHPRESDWDESCLGDRLNGILLQLISC
LQCRRCPHYFLPNLDLFQGKPHSALENAAKQTWRLAREILTNPKSLEKL
3D structure
PDB5eom Structural and biochemical characterization of the cell fate determining nucleotidyltransferase fold protein MAB21L1.
ChainA
Resolution2.55 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.7.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CTP A R23 K24 I27 I31 R62 Y63 L66 V68 K248 S252 K255 R23 K24 I27 I31 R61 Y62 L65 V67 K238 S242 K245 PDBbind-CN: -logKd/Ki=6.39,Kd=0.41uM
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0001654 eye development
GO:0008283 cell population proliferation
GO:0008284 positive regulation of cell population proliferation
GO:0009653 anatomical structure morphogenesis
GO:0043010 camera-type eye development
Cellular Component
GO:0005634 nucleus

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5eom, PDBe:5eom, PDBj:5eom
PDBsum5eom
PubMed27271801
UniProtQ13394|MB211_HUMAN Putative nucleotidyltransferase MAB21L1 (Gene Name=MAB21L1)

[Back to BioLiP]