Structure of PDB 5en1 Chain A

Receptor sequence
>5en1A (length=184) Species: 9606 (Homo sapiens) [Search protein sequence]
RKKREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRS
RGFGFVTFSSMAEVDAAMAARPHSIDGRVVEPKRAVAREESGKPGAHVTV
KKLFVGGIKEDTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFD
DHDPVDKIVLQKYHTINGHNAEVRKALSRQEMQE
3D structure
PDB5en1 Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1
ChainA
Resolution2.58 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A K22 F24 D49 V51 M53 F64 F66 A96 V97 R99 H108 K11 F13 D38 V40 M42 F53 F55 A85 V86 R88 H97 PDBbind-CN: Kd=276.2nM
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:5en1, PDBe:5en1, PDBj:5en1
PDBsum5en1
PubMed
UniProtP22626|ROA2_HUMAN Heterogeneous nuclear ribonucleoproteins A2/B1 (Gene Name=HNRNPA2B1)

[Back to BioLiP]