Structure of PDB 5ejw Chain A

Receptor sequence
>5ejwA (length=80) Species: 10090 (Mus musculus) [Search protein sequence]
HHSSGLVPRGSHMELSAIGEQVFAVESIRKKRVRKGKVEYLVKWKGWPPK
YSTWEPEEHILDPRLVMAYEEKEERDRASG
3D structure
PDB5ejw Structure-Guided Discovery of Selective Antagonists for the Chromodomain of Polycomb Repressive Protein CBX7.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 5PZ A F11 W32 W35 F23 W44 W47 PDBbind-CN: -logKd/Ki=3.30,Kd=500uM
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:5ejw, PDBe:5ejw, PDBj:5ejw
PDBsum5ejw
PubMed27326334
UniProtQ8VDS3|CBX7_MOUSE Chromobox protein homolog 7 (Gene Name=Cbx7)

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