Structure of PDB 5eiv Chain A

Receptor sequence

>5eivA (length=181) Species: 9606 (Homo sapiens) [Search protein sequence]

HPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVS
SELAEFFLEEVTPAQGGSYRCCYRRPDWGPGVWSQPSDVLELLVTEELPR
PSLVALPANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTLLG
ARAPGTYSCYYHTPSAPYVLSQRSEVLVIAA

3D structure

PDB

5eiv Structural basis for collagen recognition by the immune receptor OSCAR.

Chain

Resolution

2.414 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	peptide	A	N23 V24 T25 L62 E63	N19 V20 T21 L58 E59
BS02	peptide	A	R51 E59 F61	R47 E55 F57
BS03	peptide	A	Y137 R138 E139 T167 S169 Y171 H173 Y179 R184 V187	Y126 R127 E128 T156 S158 Y160 H162 Y168 R173 V176
BS04	peptide	A	V135 Y137 A142 P144 Y147 H173	V124 Y126 A131 P133 Y136 H162
BS05	peptide	A	R124 W154	R113 W143
BS06	peptide	A	L110 R124	L106 R113

External links

PDB	RCSB:5eiv, PDBe:5eiv, PDBj:5eiv
PDBsum	5eiv
PubMed	26552697
UniProt	Q8IYS5\|OSCAR_HUMAN Osteoclast-associated immunoglobulin-like receptor (Gene Name=OSCAR)

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