Structure of PDB 5eht Chain A

Receptor sequence
>5ehtA (length=253) Species: 1428 (Bacillus thuringiensis) [Search protein sequence]
GHMATVKKLYFVPAGRCMLDHSFVNSALTPGKLLNVPVWCYLLETEEGPI
LVDTGMPESAVNNEGLCNGTFGEGQILPKMTEEDRIVNILKRVGYEPDDL
LYIISSHLHFDHAGGNGAFTNTPIIVQRTEYEAALHREEYMTECILPHLN
YKIIEGDYEVVPGVQLLYTPGHSPGHQSLFIETEQSGSVLLTIDASYTKE
NFEDEVPFAGFDPELALSSIKRLKEVVKKEKPMIFFGHDIEQEKSCRVFP
EYI
3D structure
PDB5eht Conformational Tinkering Drives Evolution of a Promiscuous Activity through Indirect Mutational Effects.
ChainA
Resolution1.29 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.1.81: quorum-quenching N-acyl-homoserine lactonase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A D108 H109 D191 H235 D111 H112 D194 H238
BS02 ZN A H104 H106 H169 H107 H109 H172
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
GO:0102007 acyl-L-homoserine-lactone lactonohydrolase activity
Biological Process
GO:1901335 lactone catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5eht, PDBe:5eht, PDBj:5eht
PDBsum5eht
PubMed27444875
UniProtA3FJ64|AHLL_BACTU N-acyl homoserine lactonase (Gene Name=aiiA)

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