Structure of PDB 5egv Chain A

Receptor sequence
>5egvA (length=229) Species: 9606 (Homo sapiens) [Search protein sequence]
NSLALSLTADQMVSALLDAEPPILYSEFSEASMMGLLTNLADRELVHMIN
WAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLL
LDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVY
TEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSN
KGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB5egv Predictive features of ligand-specific signaling through the estrogen receptor.
ChainA
Resolution2.863 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I358 K362 V376 E380 L539 E542 M543 I49 K53 V67 E71 L220 E223 M224
BS02 5OS A L346 T347 L349 A350 E353 L387 M388 L37 T38 L40 A41 E44 L78 M79 BindingDB: EC50=266nM
External links
PDB RCSB:5egv, PDBe:5egv, PDBj:5egv
PDBsum5egv
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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