Structure of PDB 5egp Chain A

Receptor sequence
>5egpA (length=282) Species: 1437362 (Aspergillus fumigatus Z5) [Search protein sequence]
YIQNMFQTKSFVDRYKYTEKLTGLYAQTLVDYSGVANTSQKPLVVLDNAC
GIGAVSSVLNHTLQDEAKKTWKLTCGDLSEGMLETTKRRLQDEGWVNAET
KIVNALDTGLPDGHYTHVFVAFGFQSFPDANAALKECFRILASGGILASS
TWQNFNWIPIMKAAIETIPGNLPFPTQKEFITLHNAGWDSESYIQSELEK
LGFRDVKVIPVPKETSIPIDEFFEVCMMIIPYLLPKFWTEEQRESHEKDV
PMVLRQYLQDTYGANGQVPLEAVALITTGLKP
3D structure
PDB5egp Sequential Inactivation of Gliotoxin by the S-Methyltransferase TmtA.
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.9: thiol S-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH A F11 Y20 T27 A54 C55 G56 D82 L83 N109 A110 A126 F127 F132 F6 Y15 T22 A49 C50 G51 D77 L78 N104 A105 A121 F122 F127
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
Biological Process
GO:0032259 methylation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5egp, PDBe:5egp, PDBj:5egp
PDBsum5egp
PubMed26808594
UniProtQ4X158|TMTA_ASPFU Gliotoxin thiomethyltransferase GtmA (Gene Name=tmtA)

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