Structure of PDB 5egh Chain A

Receptor sequence
>5eghA (length=392) Species: 10090 (Mus musculus) [Search protein sequence]
RKLLVLLLDGFRSDYISEDALASLPGFREIVNRGVKVDYLTPDFPSLSYP
NYYTLMTGRHCEVHQMIGNYMWDPRTNKSFDIGVNRDSLMPLWWNGSEPL
WITLMKARRKVYMYYWPGCEVEILGVRPTYCLEYKTVPTDINFANAVSDA
LDSLKSGRADLAAIYHERIDVEGHHYGPSSPQRKDALRAVDTVLKYMIQW
IQDRGLQQDLNVILFSDHGMTDIFWMDKVIELSNYISLDDLQQVKDRGPV
VSLWPVPGKHSEIYHKLRTVEHMTVYEKESIPNRFYYKKGKFVSPLTLVA
DEGWFIAESREMLPFWMNSTGKREGWQRGWHGYDNELMDMRGIFLAIGPD
FKSNFRAAPIRSVDVYNIMAHVAGITPLPNNGSWSRVVSMLK
3D structure
PDB5egh Structure and biological function of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase
ChainA
Resolution1.803 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.4.-
3.1.4.38: glycerophosphocholine cholinephosphodiesterase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FUL A G348 W349 R351 G325 W326 R328
BS02 ZN A D193 H197 H354 D170 H174 H331
BS03 ZN A D32 D240 H241 D9 D217 H218
BS04 PC A D32 S71 Y75 Y157 Y188 E190 D193 H241 H354 D9 S48 Y52 Y134 Y165 E167 D170 H218 H331
External links
PDB RCSB:5egh, PDBe:5egh, PDBj:5egh
PDBsum5egh
PubMed26888014
UniProtQ8BGN3|ENPP6_MOUSE Glycerophosphocholine cholinephosphodiesterase ENPP6 (Gene Name=Enpp6)

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