Structure of PDB 5ef6 Chain A

Receptor sequence
>5ef6A (length=61) Species: 9606 (Homo sapiens) [Search protein sequence]
RKKRIPYSKGQLRELEREYAANKFITKDKRRKISAATSLSERQITIWFQN
RRVKEKKVLAK
3D structure
PDB5ef6 Impact of cytosine methylation on DNA binding specificities of human transcription factors.
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R217 R220 Y223 R258 Q259 I262 N266 K270 R1 R4 Y7 R42 Q43 I46 N50 K54
BS02 dna A R217 R220 P222 F240 K243 R246 Q265 R268 R1 R4 P6 F24 K27 R30 Q49 R52
BS03 dna A T242 K243 T26 K27
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:5ef6, PDBe:5ef6, PDBj:5ef6
PDBsum5ef6
PubMed28473536
UniProtQ92826|HXB13_HUMAN Homeobox protein Hox-B13 (Gene Name=HOXB13)

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