Structure of PDB 5e9n Chain A

Receptor sequence

>5e9nA (length=495) Species: 627145 (Steccherinum murashkinskyi)

AQIGPVTDLHITNANISPDGFSRPAVLAGGTFPGPTIAGNTGDNFQITVF
NDLTDPSMLTDTSIHWHGLFQKGTNWADGPAFVTQCPIITGQSFDYNFNV
PGQAGTFWYHSHLSTQYCDGLRGPFVVYDPNDPNASLYDVDDDTTIITLA
DWYHTLAQQEPIGAAITADATLINGLGRSFTNTTASPLSVITVQSGKRYR
MRLVSISCDPNYLFSIDGHDMTIIEVDGVNSQQLTVDQIQIFAAQRYSFV
LNANQPVGNYWIRAQPNSGGQGFDGGINSAILRYEGATVEDPTTTAPTTF
SNPLVETDLHPLADLGVPGQPFRGGADDPLVLNLAFANGRFSIDGVSFVP
PTVPVLLQILSGAQNAQDLLPAGSVISLPSNSVIEVALPAGAAGGPHPFH
LHGHNFAVVQSANNATPNYVNPIWRDTVSIGGTGDNVTIRFTTNNPGPWF
LHCHIDWHLEAGFAIVFAEDIPDTASANPVPQAWSDLCPAYDQAH

3D structure

• PDB: 5e9n Structure-function study of two new middle-redox potential laccases from basidiomycetes Antrodiella faginea and Steccherinum murashkinskyi.
• Chain: A
• Resolution: 0.95 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): H65 H67 H110 H112 H397 H400 H402 H452 C453 H454 I455 H458 F463
• Catalytic site (residue number reindexed from 1): H65 H67 H110 H112 H397 H400 H402 H452 C453 H454 I455 H458 F463
• Enzyme Commision number: 1.10.3.2: laccase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	CU	A	H112 H402 H452	H112 H402 H452
BS02	CU	A	H67 H110 H454	H67 H110 H454
BS03	CU	A	H65 H400 H402	H65 H400 H402
BS04	CU	A	H397 C453 H458	H397 C453 H458

Gene Ontology

Molecular Function

• GO:0005507 copper ion binding
• GO:0016491 oxidoreductase activity
• GO:0046872 metal ion binding
• GO:0052716 hydroquinone:oxygen oxidoreductase activity

Cellular Component

• GO:0005576 extracellular region

External links

• PDB: RCSB:5e9n, PDBe:5e9n, PDBj:5e9n
• PDBsum: 5e9n
• PubMed: 29890251
• UniProt: I1VE66