Structure of PDB 5e89 Chain A

Receptor sequence
>5e89A (length=137) Species: 9606 (Homo sapiens) [Search protein sequence]
LIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRF
NENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAV
NDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
3D structure
PDB5e89 Galectin-3-Binding Glycomimetics that Strongly Reduce Bleomycin-Induced Lung Fibrosis and Modulate Intracellular Glycan Recognition.
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TD2 A R144 A146 H158 R162 E165 W181 E184 R186 R31 A33 H45 R49 E52 W68 E71 R73 MOAD: Kd=0.014uM
PDBbind-CN: -logKd/Ki=7.85,Kd=0.014uM
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding

View graph for
Molecular Function
External links
PDB RCSB:5e89, PDBe:5e89, PDBj:5e89
PDBsum5e89
PubMed27356186
UniProtP17931|LEG3_HUMAN Galectin-3 (Gene Name=LGALS3)

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