Structure of PDB 5e7n Chain A

Receptor sequence
>5e7nA (length=123) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHMVGQLSRGAIAAIMQKGDTNIKPILQVINIRPITTGNSPPRYRLLMS
DGLNTLSSFMLATQLNPLVEEEQLSSNCVCQIHRFIVNTLKDGRRVVILM
ELEVLKSAEAVGVKIGNPVPYNE
3D structure
PDB5e7n Identification and Optimization of Anthranilic Acid Based Inhibitors of Replication Protein A.
ChainA
Resolution1.21 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5KR A I33 R41 R43 S55 M57 I83 N85 L87 I95 I36 R44 R46 S58 M60 I86 N88 L90 I98 MOAD: Kd=30uM
PDBbind-CN: -logKd/Ki=6.09,Kd=0.81uM
Gene Ontology
Biological Process
GO:0006260 DNA replication
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5e7n, PDBe:5e7n, PDBj:5e7n
PDBsum5e7n
PubMed26748787
UniProtP27694|RFA1_HUMAN Replication protein A 70 kDa DNA-binding subunit (Gene Name=RPA1)

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