Structure of PDB 5e73 Chain A

Receptor sequence
>5e73A (length=116) Species: 9606 (Homo sapiens) [Search protein sequence]
SMSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVI
KKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGH
NMRKYFEKKWTDTFKV
3D structure
PDB5e73 The "Gatekeeper" Residue Influences the Mode of Binding of Acetyl Indoles to Bromodomains.
ChainA
Resolution1.71 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UO1 A W1887 P1888 V1893 V1898 I1950 W32 P33 V38 V43 I95 MOAD: Kd=23uM
PDBbind-CN: -logKd/Ki=4.64,Kd=23uM
BindingDB: Kd=23000nM
External links
PDB RCSB:5e73, PDBe:5e73, PDBj:5e73
PDBsum5e73
PubMed26982797
UniProtQ9UIF8|BAZ2B_HUMAN Bromodomain adjacent to zinc finger domain protein 2B (Gene Name=BAZ2B)

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