Structure of PDB 5e6r Chain A

Receptor sequence
>5e6rA (length=581) Species: 9606 (Homo sapiens) [Search protein sequence]
YNLDVRGARSFSPPRAGRHFGYRVLQVGNGVIVGAPGEGNSTGSLYQCQS
GTGHCLPVTLRGSNYTSKYLGMTLATDPTDGSILACDPGLSRTCDQNTYL
SGLCYLFRQNLQGPMLQGRPGFQECIKGNVDLVFLFDGSMSLQPDEFQKI
LDFMKDVMKKLSNTSYQFAAVQFSTSYKTEFDFSDYVKWKDPDALLKHVK
HMLLLTNTFGAINYVATEVFREELGARPDATKVLIIITDGEATDSGNIDA
AKDIIRYIIGIGKHFQTKESQETLHKFASKPASEFVKILDTFEKLKDLFT
ELQKKIDLTSFNMELSSSGISADLSRGHAVVGAVGAKDWAGGFLDLKADL
QDDTFIGNEPLTPEVRAGYLGYTVTWLPSRQKTSLLASGAPRYQHMGRVL
LFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPL
FYGEQRGGRVFIYQRRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGD
GLVDVAVGAPLEEQGAVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRS
IHGVKDLEGDGLADVAVGAESQMIVLSSRPV
3D structure
PDB5e6r Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops.
ChainA
Resolution2.901 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D137 S139 S141 T206 D239 D137 S139 S141 T206 D239
BS02 CA A D443 D445 D447 E449 E451 D434 D436 D438 E440 E442
BS03 CA A D505 N507 D509 L511 D513 D496 N498 D500 L502 D504
Gene Ontology
Cellular Component
GO:0008305 integrin complex

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5e6r, PDBe:5e6r, PDBj:5e6r
PDBsum5e6r
PubMed26936951
UniProtP20701|ITAL_HUMAN Integrin alpha-L (Gene Name=ITGAL)

[Back to BioLiP]