Structure of PDB 5e68 Chain A

Receptor sequence
>5e68A (length=167) Species: 90370 (Salmonella enterica subsp. enterica serovar Typhi) [Search protein sequence]
LLDSFAVDHTRMQAPAVRTAKTMNTPHGDAITVFDLRFCIPNKEVMPEKG
IHTLEHLFAGFMRDHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVAD
AWKAAMADVLKVQDQNQIPELNVYQCGTYQMHSLSEAQDIARHILERDVR
VNSNKELALPKEKLQEL
3D structure
PDB5e68 High resolution crystal structure of LuxS - Quorum sensor molecular complex from Salmonella typhi at 1.58 Angstroms
ChainA
Resolution1.58 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 4.4.1.21: S-ribosylhomocysteine lyase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A H54 H58 C128 H52 H56 C126
BS02 PAV A P80 M81 G82 R84 P78 M79 G80 R82
BS03 MET A L3 Y88 L1 Y86
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0016829 lyase activity
GO:0043768 S-ribosylhomocysteine lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0009372 quorum sensing

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:5e68, PDBe:5e68, PDBj:5e68
PDBsum5e68
PubMed
UniProtQ8Z4D7|LUXS_SALTI S-ribosylhomocysteine lyase (Gene Name=luxS)

[Back to BioLiP]