Structure of PDB 5e66 Chain A

Receptor sequence
>5e66A (length=424) Species: 1173138 (Influenza D virus (D/swine/Oklahoma/1334/2011)) [Search protein sequence]
ELICIVQRVNESFSLHSGFGGNVYSMKTEPMTGFTNVTKGASVINQKDWI
GFGDSRTDLTNDQFPASSDVPLAVAKKFRSLSGASLMLSAFGPPGKVDYL
YQGCGKEKVFYEGVNWSPEAGIDCFGSNWTQTKKDFYSRIYEAARSSTCM
TLVNSLDTKISSTTATAGTASSCSSSWMKSPLWYAESSVNPPQVCGTEQS
ATFTLPTSFGIYKCNKHVVQLCYFVYENKAKFNTFGCGDYYQNYYDGNGN
LIGGMDNRVAAYRGIANAGVKIECPSKILNPGTYSIKSTPRFLLVPKRSY
CFDTDGGYPIQVVQSEWSASRRSDNATEEACLQTEGCIFIKKTTPYVGEA
DDNHGDIEMRQLLSGLGNNDTVCVSQSGYTKGETPFVKDYLSPPKYGRCQ
LKTDSGRIPTLPSGLIIPQAGTDS
3D structure
PDB5e66 An Open Receptor-Binding Cavity of Hemagglutinin-Esterase-Fusion Glycoprotein from Newly-Identified Influenza D Virus: Basis for Its Broad Cell Tropism
ChainA
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.1.53: sialate O-acetylesterase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5KQ A N63 Q65 R326 D356 H359 N61 Q63 R321 D351 H354
BS02 5KQ A A172 S173 F229 Y231 V275 F297 A170 S171 F224 Y226 V270 F292
Gene Ontology
Molecular Function
GO:0016788 hydrolase activity, acting on ester bonds
GO:0046789 host cell surface receptor binding
Biological Process
GO:0019064 fusion of virus membrane with host plasma membrane
Cellular Component
GO:0019031 viral envelope

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5e66, PDBe:5e66, PDBj:5e66
PDBsum5e66
PubMed26816272
UniProtK9LG83

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