Structure of PDB 5e5u Chain A

Receptor sequence
>5e5uA (length=264) Species: 10090 (Mus musculus) [Search protein sequence]
DPYWAYSGAYGPEHWVTSSVSCGGSHQSPIDILDHHARVGDEYQELQLDG
FDNESSNKTWMKNTGKTVAILLKDDYFVSGAGLPGRFKAEKVEFHWGHSN
GSAGSEHSVNGRRFPVEMQIFFYNPDDFDSFQTAISENRIIGAMAIFFQV
SPRDNSALDPIIHGLKGVVHHEKETFLDPFILRDLLPASLGSYYRYTGSL
TTPPCSEIVEWIVFRRPVPISYHQLEAFYSIFTTEQQDHVKSVEYLRNNF
RPQQALNDRVVSKS
3D structure
PDB5e5u Structural Basis for Interactions Between Contactin Family Members and Protein-tyrosine Phosphatase Receptor Type G in Neural Tissues.
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) K122 E149 H151 E162 Q175 T257
Catalytic site (residue number reindexed from 1) K66 E93 H95 E106 Q119 T201
Enzyme Commision number 3.1.3.48: protein-tyrosine-phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1PS A W116 E230 F232 W60 E174 F176
BS02 1PS A H91 H92 H35 H36
Gene Ontology
Molecular Function
GO:0004089 carbonate dehydratase activity
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:5e5u, PDBe:5e5u, PDBj:5e5u
PDBsum5e5u
PubMed27539848
UniProtQ05909|PTPRG_MOUSE Receptor-type tyrosine-protein phosphatase gamma (Gene Name=Ptprg)

[Back to BioLiP]