Structure of PDB 5e15 Chain A

Receptor sequence
>5e15A (length=218) Species: 9606 (Homo sapiens) [Search protein sequence]
KNSLALSLTADQMVSALLDAEPPILYSEYSMMGLLTNLADRELVHMINWA
KRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLD
RNQMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVKDHIHRVLD
KITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKC
KNVVPLSDLLLEMLDAHR
3D structure
PDB5e15 Predictive features of ligand-specific signaling through the estrogen receptor.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A I358 K362 V376 L539 E542 I47 K51 V65 L209 E212
BS02 5KA A L346 T347 A350 E353 L387 F404 L35 T36 A39 E42 L76 F93
External links
PDB RCSB:5e15, PDBe:5e15, PDBj:5e15
PDBsum5e15
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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