Structure of PDB 5e14 Chain A

Receptor sequence
>5e14A (length=232) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTFSEASMMGLLTNLADRELVH
MINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAP
NLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNS
GVYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRH
MSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB5e14 Predictive features of ligand-specific signaling through the estrogen receptor.
ChainA
Resolution2.22 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A I358 V376 E380 D538 L539 E542 I52 V70 E74 D222 L223 E226
BS02 5KB A E353 F404 G420 M421 H524 L525 E47 F98 G114 M115 H208 L209
External links
PDB RCSB:5e14, PDBe:5e14, PDBj:5e14
PDBsum5e14
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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