Structure of PDB 5e0x Chain A

Receptor sequence
>5e0xA (length=230) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSH
IRHMSNKGMEHLYSMKPLSDLLLEMLDAHR
3D structure
PDB5e0x Predictive features of ligand-specific signaling through the estrogen receptor.
ChainA
Resolution2.014 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A I358 K362 L372 V376 L379 D538 L539 E542 I54 K58 L68 V72 L75 D220 L221 E224
BS02 5KD A M343 E353 L387 M421 H524 L525 K529 M39 E49 L83 M117 H211 L212 K216
External links
PDB RCSB:5e0x, PDBe:5e0x, PDBj:5e0x
PDBsum5e0x
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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