Structure of PDB 5dzi Chain A

Receptor sequence
>5dziA (length=235) Species: 9606 (Homo sapiens) [Search protein sequence]
NSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRE
LVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLL
FAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIIL
LNSGVYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSH
IRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB5dzi Predictive features of ligand-specific signaling through the estrogen receptor.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A I358 N359 K362 R363 L372 V376 E380 D538 L539 E542 I55 N56 K59 R60 L69 V73 E77 D225 L226 E229
BS02 5KF A T347 A350 E353 L387 H524 L525 T44 A47 E50 L84 H211 L212
External links
PDB RCSB:5dzi, PDBe:5dzi, PDBj:5dzi
PDBsum5dzi
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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