Structure of PDB 5dyb Chain A

Receptor sequence
>5dybA (length=229) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYTRPFSEASMMGLLTNLADRELVH
MINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAP
NLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNS
GVYDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSN
KGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB5dyb Predictive features of ligand-specific signaling through the estrogen receptor.
ChainA
Resolution2.27 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A I358 K362 L372 V376 L379 E380 D538 L539 E542 I52 K56 L66 V70 L73 E74 D219 L220 E223
BS02 5K2 A T347 A350 E353 L387 M421 I424 L428 L525 T41 A44 E47 L81 M115 I118 L122 L206
External links
PDB RCSB:5dyb, PDBe:5dyb, PDBj:5dyb
PDBsum5dyb
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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