Structure of PDB 5dy8 Chain A

Receptor sequence
>5dy8A (length=233) Species: 9606 (Homo sapiens) [Search protein sequence]
NSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRE
LVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLL
FAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIIL
LNSGVYKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIR
HMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB5dy8 Predictive features of ligand-specific signaling through the estrogen receptor.
ChainA
Resolution2.031 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A I358 K362 V376 E380 D538 L539 E542 I55 K59 V73 E77 D223 L224 E227
BS02 5K4 A T347 A350 E353 L387 F404 M421 L525 T44 A47 E50 L84 F101 M118 L210
External links
PDB RCSB:5dy8, PDBe:5dy8, PDBj:5dy8
PDBsum5dy8
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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