Structure of PDB 5dxq Chain A

Receptor sequence
>5dxqA (length=227) Species: 9606 (Homo sapiens) [Search protein sequence]
LALSLTADQMVSALLDAEPPILYSEYFSEASMMGLLTNLADRELVHMINW
AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLL
DRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYT
FKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNK
GMEHLYSMKCKNVPLSDLLLEMLDAHR
3D structure
PDB5dxq Predictive features of ligand-specific signaling through the estrogen receptor.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I358 K362 V376 L379 E380 D538 E542 I48 K52 V66 L69 E70 D217 E221
BS02 5HZ A L346 T347 A350 E353 M388 F404 M421 L525 L36 T37 A40 E43 M78 F94 M111 L205
External links
PDB RCSB:5dxq, PDBe:5dxq, PDBj:5dxq
PDBsum5dxq
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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