Structure of PDB 5dxp Chain A

Receptor sequence
>5dxpA (length=222) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDSMMGLLTNLADRELVHMINWAK
RVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDR
NQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYDHI
HRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHL
YSMKCKNVVPLSDLLLEMLDAH
3D structure
PDB5dxp Predictive features of ligand-specific signaling through the estrogen receptor.
ChainA
Resolution2.201 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I358 K362 Q375 V376 L379 E380 E542 M543 I46 K50 Q63 V64 L67 E68 E217 M218
BS02 5HX A L346 A350 E353 F404 L34 A38 E41 F92
External links
PDB RCSB:5dxp, PDBe:5dxp, PDBj:5dxp
PDBsum5dxp
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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