Structure of PDB 5dxk Chain A

Receptor sequence
>5dxkA (length=234) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHI
RHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB5dxk Predictive features of ligand-specific signaling through the estrogen receptor.
ChainA
Resolution2.226 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I358 K362 V376 E380 D538 L539 E542 I54 K58 V72 E76 D224 L225 E228
BS02 5J1 A L346 T347 A350 E353 M388 F404 M421 L525 L42 T43 A46 E49 M84 F100 M117 L211
External links
PDB RCSB:5dxk, PDBe:5dxk, PDBj:5dxk
PDBsum5dxk
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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