Structure of PDB 5dwj Chain A

Receptor sequence
>5dwjA (length=231) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPFSEASMMGLLTNLADRELVHM
INWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPN
LLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSG
VYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHM
SNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB5dwj Predictive features of ligand-specific signaling through the estrogen receptor.
ChainA
Resolution2.001 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I358 K362 L372 V376 E380 D538 L539 E542 M543 I51 K55 L65 V69 E73 D221 L222 E225 M226
BS02 5J2 A L346 T347 A350 E353 L387 M421 I424 H524 L525 L39 T40 A43 E46 L80 M114 I117 H207 L208 BindingDB: EC50=10.0nM
External links
PDB RCSB:5dwj, PDBe:5dwj, PDBj:5dwj
PDBsum5dwj
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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