Structure of PDB 5dwi Chain A

Receptor sequence
>5dwiA (length=232) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTFSEASMMGLLTNLADRELVH
MINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAP
NLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNS
GVYTEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRH
MSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB5dwi Predictive features of ligand-specific signaling through the estrogen receptor.
ChainA
Resolution2.43 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I358 K362 V376 D538 L539 E542 I52 K56 V70 D222 L223 E226
BS02 5G3 A L346 T347 A350 E353 L387 M421 G521 L525 L40 T41 A44 E47 L81 M115 G205 L209 BindingDB: EC50=0.100000nM
External links
PDB RCSB:5dwi, PDBe:5dwi, PDBj:5dwi
PDBsum5dwi
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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