Structure of PDB 5dwg Chain A

Receptor sequence
>5dwgA (length=225) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEFSEASMMGLLTNLADRELVHMINW
AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLL
DRNQGKCVEMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTK
DHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGM
EHLYSMKCKNVPLSDLLLEMLDAHR
3D structure
PDB5dwg Predictive features of ligand-specific signaling through the estrogen receptor.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A I358 V376 L539 E542 I48 V66 L216 E219
BS02 5G4 A L346 T347 A350 E353 L387 F404 M421 L525 L36 T37 A40 E43 L77 F94 M110 L203
External links
PDB RCSB:5dwg, PDBe:5dwg, PDBj:5dwg
PDBsum5dwg
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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