Structure of PDB 5dw5 Chain A

Receptor sequence
>5dw5A (length=512) Species: 1457393 (Acetobacter aceti 1023) [Search protein sequence]
ERIRNVALRSKVCPAETASELIKHGDVVGTSGFTGAGYPKEVPKALAQRM
EAAHDRGEKYQISLITGASTGPQLDGELAKANGVYFRSPFNTDATMRNRI
NAGETEYFDNHLGQVAGRAVQGNYGKFNIALVEATAITEDGGIVPTSSVG
NSQTFLNLAEKVIIEVNEWQNPMLEGIHDIWDGNVSGVPTRDIVPIVRAD
QRVGGPVLRVNPDKIAAIVRTNDRDRNAPFAAPDETAKAIAGYLLDFFGH
EVKQNRLPPSLLPLQSGVGNVANAVLEGLKEGPFENLVGYSEVIQDGMLA
MLDSGRMRIASASSFSLSPEAAEEINNRMDFFRSKIILRQQDVSNSPGII
RRLGCIAMNGMIEADIYGNVNSTRVMGSKMMNGIGGSGDFARSSYLSIFL
SPSTAKGGKISAIVPMAAHVDHIMQDAQIFVTEQGLADLRGLSPVQRARE
IISKCAHPDYRPMLQDYFDRALKNSFGKHTPHLLTEALSWHQRFIDTGTM
LPSSLEHHHHHH
3D structure
PDB5dw5 Functional Dissection of the Bipartite Active Site of the Class I Coenzyme A (CoA)-Transferase Succinyl-CoA:Acetate CoA-Transferase.
ChainA
Resolution1.656 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.8.3.18: succinyl-CoA:acetate CoA-transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 0T1 A Q267 E294 N361 M363 I364 G385 G388 S389 A407 I412 Q265 E292 N359 M361 I362 G383 G386 S387 A405 I410
BS02 ACT A F110 N112 N125 Y126 F108 N110 N123 Y124
Gene Ontology
Molecular Function
GO:0003986 acetyl-CoA hydrolase activity
GO:0008410 CoA-transferase activity
GO:0008775 acetate CoA-transferase activity
GO:0016740 transferase activity
Biological Process
GO:0006083 acetate metabolic process
GO:0006084 acetyl-CoA metabolic process
GO:0006085 acetyl-CoA biosynthetic process
GO:0019427 acetyl-CoA biosynthetic process from acetate
GO:0045733 acetate catabolic process
GO:1901289 succinyl-CoA catabolic process

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5dw5, PDBe:5dw5, PDBj:5dw5
PDBsum5dw5
PubMed27242998
UniProtB3EY95|SCACT_ACEAC Succinyl-CoA:acetate CoA-transferase

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