Structure of PDB 5dvv Chain A

Receptor sequence
>5dvvA (length=209) Species: 9606 (Homo sapiens) [Search protein sequence]
LTADQMVSALLDAEPPILYSEASMMGLLTNLADRELVHMINWAKRVPGFV
DLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRVEIFDM
LLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTKSLEEKDHIHRVLDKIT
DTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSVPLSDL
LLEMLDAHR
3D structure
PDB5dvv Predictive features of ligand-specific signaling through the estrogen receptor.
ChainA
Resolution2.505 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A I358 V376 D538 L539 E542 M543 I40 V58 D199 L200 E203 M204
BS02 5G6 A T347 A350 E353 L387 G521 L525 T29 A32 E35 L69 G188 L192 BindingDB: EC50=3.0nM
External links
PDB RCSB:5dvv, PDBe:5dvv, PDBj:5dvv
PDBsum5dvv
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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