Structure of PDB 5du5 Chain A

Receptor sequence
>5du5A (length=231) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYPFSEASMMGLLTNLADRELVHMI
NWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNL
LLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGV
YTFEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHM
SNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB5du5 Predictive features of ligand-specific signaling through the estrogen receptor.
ChainA
Resolution2.195 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A I358 K362 V376 D538 L539 E542 I50 K54 V68 D221 L222 E225
BS02 5G2 A L346 T347 A350 E353 L387 M388 L525 L38 T39 A42 E45 L79 M80 L208
External links
PDB RCSB:5du5, PDBe:5du5, PDBj:5du5
PDBsum5du5
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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