Structure of PDB 5dtv Chain A

Receptor sequence
>5dtvA (length=230) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPFSEASMMGLLTNLADRELVHM
INWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPN
LLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSG
VYTKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMS
NKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB5dtv Predictive features of ligand-specific signaling through the estrogen receptor.
ChainA
Resolution2.295 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A I358 K362 H373 L539 E542 I51 K55 H66 L221 E224
BS02 5FS A L346 T347 L349 A350 E353 F404 F425 L525 L39 T40 L42 A43 E46 F97 F118 L207
External links
PDB RCSB:5dtv, PDBe:5dtv, PDBj:5dtv
PDBsum5dtv
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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