Structure of PDB 5drj Chain A

Receptor sequence
>5drjA (length=234) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHI
RHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB5drj Predictive features of ligand-specific signaling through the estrogen receptor.
ChainA
Resolution2.07 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I358 K362 L372 V376 E380 D538 L539 E542 I54 K58 L68 V72 E76 D224 L225 E228
BS02 5EU A M343 L346 E353 L387 M421 G521 H524 M39 L42 E49 L83 M117 G207 H210 BindingDB: EC50=101nM
External links
PDB RCSB:5drj, PDBe:5drj, PDBj:5drj
PDBsum5drj
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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