Structure of PDB 5dnj Chain A

Receptor sequence
>5dnjA (length=215) Species: 10090 (Mus musculus) [Search protein sequence]
HLSDLLQQLTSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYG
LGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSL
MKKITLLNYFRNYMSEHLLKAGANITPRELPYLRTWFRTRSAIILHLSNG
TVQINFFQDHTKLILCPLMAAVTYINEKRDFQTYRLSLLEEYGCCKELAS
RLRYARTMVDKLLSS
3D structure
PDB5dnj Structural basis for recognition of Emi2 by Polo-like kinase 1 and development of peptidomimetics blocking oocyte maturation and fertilization.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.21: polo kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A W414 D416 Y417 Y421 Y481 Y485 L490 L491 H538 K540 W42 D44 Y45 Y49 Y109 Y113 L118 L119 H160 K162
External links
PDB RCSB:5dnj, PDBe:5dnj, PDBj:5dnj
PDBsum5dnj
PubMed26459104
UniProtQ07832|PLK1_MOUSE Serine/threonine-protein kinase PLK1 (Gene Name=Plk1)

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