Structure of PDB 5dnd Chain A

Receptor sequence
>5dndA (length=353) Species: 10141 (Cavia porcellus) [Search protein sequence]
ERHLLLIYTGGTLGMQSKGGVLVPGPGLVTLLRTLPMFHDKEFAQAQGLP
DHALALPPASHGPRVLYTVLECQPLLDSSDMTIDDWIRIAKIIERHYEQY
QGFVVIHGADTMASGASMLSFMLENLHKPVILTGAQVPIRVLWNDARENL
LGALLVAGQYIIPEVCLFMNSQLFRGNRVTKVDSQKFEAFCSPLSPLATV
GADVTIAWDLVRKVKWKDPLVVHSNMEHDVALLRLYPGIPASLVRAFLQP
PLKGVVLETFGSGNGPSKPDLLQELRAAAQRGLIMVNCSQCLRGSVTPGY
ATSLAGANIVSGLDMTSEAALAKLSYVLGLPELSLERRQELLAKDLRGEM
TLP
3D structure
PDB5dnd Experimental Data in Support of a Direct Displacement Mechanism for Type I/II l-Asparaginases.
ChainA
Resolution2.29 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) T19 V28 A116 D117 K188
Catalytic site (residue number reindexed from 1) T12 V21 A109 D110 K181
Enzyme Commision number 3.5.1.1: asparaginase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ASN A T19 D84 S85 G115 A116 D117 A142 T12 D77 S78 G108 A109 D110 A135
Gene Ontology
Molecular Function
GO:0004067 asparaginase activity
Biological Process
GO:0009066 aspartate family amino acid metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5dnd, PDBe:5dnd, PDBj:5dnd
PDBsum5dnd
PubMed26733195
UniProtH0W0T5

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