Structure of PDB 5dmf Chain A

Receptor sequence
>5dmfA (length=236) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILS
HIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB5dmf Predictive features of ligand-specific signaling through the estrogen receptor.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A I358 N359 K362 R363 L372 V376 E380 E542 I54 N55 K58 R59 L68 V72 E76 E230
BS02 5DG A M343 T347 A350 E353 L387 G420 M421 G521 H524 L525 M39 T43 A46 E49 L83 G116 M117 G209 H212 L213
External links
PDB RCSB:5dmf, PDBe:5dmf, PDBj:5dmf
PDBsum5dmf
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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