Structure of PDB 5dmc Chain A

Receptor sequence
>5dmcA (length=223) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYFSEASMMGLLTNLADRELVHMIN
WAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLL
LDRNQGKCVMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTK
DHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGM
EHLYSMKCKNPLSDLLLEMLDAH
3D structure
PDB5dmc Predictive features of ligand-specific signaling through the estrogen receptor.
ChainA
Resolution2.403 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I358 K362 V376 E380 D538 E542 M543 I49 K53 V67 E71 D214 E218 M219
BS02 5DH A A350 E353 L387 F404 M421 I424 G521 L525 A41 E44 L78 F95 M110 I113 G199 L203
External links
PDB RCSB:5dmc, PDBe:5dmc, PDBj:5dmc
PDBsum5dmc
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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