Structure of PDB 5dlr Chain A

Receptor sequence
>5dlrA (length=233) Species: 9606 (Homo sapiens) [Search protein sequence]
NSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRE
LVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLL
FAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIIL
LNSGVYKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIR
HMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB5dlr Predictive features of ligand-specific signaling through the estrogen receptor.
ChainA
Resolution2.26 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A I358 K362 V376 E380 E542 I55 K59 V73 E77 E227
BS02 5DJ A L346 T347 A350 E353 L387 M421 I424 G521 L525 L43 T44 A47 E50 L84 M118 I121 G206 L210
External links
PDB RCSB:5dlr, PDBe:5dlr, PDBj:5dlr
PDBsum5dlr
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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