Structure of PDB 5dl4 Chain A

Receptor sequence
>5dl4A (length=237) Species: 9606 (Homo sapiens) [Search protein sequence]
NSLALSLTADQMVSALLDAEPPILYSEYDPPFSEASMMGLLTNLADRELV
HMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFA
PNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLN
SGVYTFEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSH
IRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRLH
3D structure
PDB5dl4 Predictive features of ligand-specific signaling through the estrogen receptor.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A I358 K362 L372 V376 E380 D538 E542 I53 K57 L67 V71 E75 D225 E229
BS02 5C4 A M343 T347 A350 E353 L387 L391 F404 M421 G521 H524 L525 M38 T42 A45 E48 L82 L86 F99 M116 G208 H211 L212
External links
PDB RCSB:5dl4, PDBe:5dl4, PDBj:5dl4
PDBsum5dl4
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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