Structure of PDB 5dks Chain A

Receptor sequence
>5dksA (length=225) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEPFSEASMMGLLTNLADRELVHMIN
WAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLL
LDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVY
TFEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMS
NKGMEHLYSMVPLSDLLLEMLDAHR
3D structure
PDB5dks Predictive features of ligand-specific signaling through the estrogen receptor.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I358 L372 V376 E380 D538 E542 I49 L63 V67 E71 D215 E219
BS02 5C6 A M342 M343 L346 T347 A350 E353 L387 G415 V418 M421 I424 F425 G521 L525 M33 M34 L37 T38 A41 E44 L78 G106 V109 M112 I115 F116 G203 L207
External links
PDB RCSB:5dks, PDBe:5dks, PDBj:5dks
PDBsum5dks
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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