Structure of PDB 5dkb Chain A

Receptor sequence

>5dkbA (length=230) Species: 9606 (Homo sapiens) [Search protein sequence]

SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHI
RHMSNKGMEHLYSMKCPLSDLLLEMLDAHR

3D structure

PDB

5dkb Predictive features of ligand-specific signaling through the estrogen receptor.

Chain

Resolution

2.4 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	peptide	A	I358 K362 L372 V376 E380 E542	I54 K58 L68 V72 E76 E224
BS02	5C9	A	M343 T347 A350 E353 L387 G420 M421 G521 H524 L525 M528	M39 T43 A46 E49 L83 G116 M117 G207 H210 L211 M214
BS03	5C9	A	M343 T347 A350 E353 L387 V418 E419 M421 G521 H524 L525	M39 T43 A46 E49 L83 V114 E115 M117 G207 H210 L211

External links

PDB	RCSB:5dkb, PDBe:5dkb, PDBj:5dkb
PDBsum	5dkb
PubMed	27107013
UniProt	P03372\|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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