Structure of PDB 5dk9 Chain A

Receptor sequence
>5dk9A (length=230) Species: 9606 (Homo sapiens) [Search protein sequence]
LALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELV
HMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFA
PNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLN
SGVYTDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHM
SNKGMEHLYSMKCNVVPLSDLLLEMLDAHR
3D structure
PDB5dk9 Predictive features of ligand-specific signaling through the estrogen receptor.
ChainA
Resolution2.28 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I358 K362 L372 V376 E380 D538 E542 I53 K57 L67 V71 E75 D220 E224
BS02 5CC A L346 T347 A350 E353 L387 F404 V418 G420 M421 I424 G521 H524 L525 M528 L41 T42 A45 E48 L82 F99 V113 G115 M116 I119 G204 H207 L208 M211
External links
PDB RCSB:5dk9, PDBe:5dk9, PDBj:5dk9
PDBsum5dk9
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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