Structure of PDB 5djh Chain A

Receptor sequence
>5djhA (length=252) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
HHHHHDDLTDAELAADLAADAGKLLLQVRAEIGFDQPWTLGEAGDRQANS
LLLRRLQAERPGDAVLSEEAHDDLARLKSDRVWIIDPLDGTREFSTPGRD
DWAVHIALWRRSPEITDAAVALPARGNVVYRTDTVTSVPGTLRIAVSATR
PPAVLHRIRQTLAIQPVSIGSAGAKAMAVIDGYVDAYLHAGGQWEWDSAA
PAGVMLAAGMHASRLDGSPLRYNQLDPYLPDLLMCRAEVAPILLGAIADA
WR
3D structure
PDB5djh Crystal Structures of Mycobacterium tuberculosis CysQ, with Substrate and Products Bound.
ChainA
Resolution1.451 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.1.3.11: fructose-bisphosphatase.
3.1.3.25: inositol-phosphate phosphatase.
3.1.3.7: 3'(2'),5'-bisphosphate nucleotidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A E73 D91 L93 E68 D86 L88
BS02 MG A D91 D94 D212 D86 D89 D197
BS03 AMP A D94 S162 R165 G185 S186 K190 H204 G206 G207 Q208 D212 D89 S147 R150 G170 S171 K175 H189 G191 G192 Q193 D197
BS04 PO4 A E73 D91 L93 D94 G95 T96 E68 D86 L88 D89 G90 T91
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0005515 protein binding
GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity
GO:0008934 inositol monophosphate 1-phosphatase activity
GO:0016787 hydrolase activity
GO:0030145 manganese ion binding
GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity
GO:0046872 metal ion binding
GO:0050897 cobalt ion binding
GO:0052832 inositol monophosphate 3-phosphatase activity
GO:0052833 inositol monophosphate 4-phosphatase activity
GO:0052834 inositol monophosphate phosphatase activity
Biological Process
GO:0000103 sulfate assimilation
GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process
Cellular Component
GO:0005886 plasma membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5djh, PDBe:5djh, PDBj:5djh
PDBsum5djh
PubMed26512869
UniProtP9WKJ1|CYSQ_MYCTU 3'-phosphoadenosine 5'-phosphate phosphatase (Gene Name=cysQ)

[Back to BioLiP]