Structure of PDB 5dir Chain A

Receptor sequence
>5dirA (length=157) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
PDVDRFGRLPWLWITVLVFVLDQVSKAFFQAELSMYQQIVVIPDLFSWTL
AYNTGAAFSFLADSSGWQRWLFALIAIVVSASLVVWLKRLKKGETWLAIA
LALVLGGALGNLYDRMVLGHVVDFILVHWQNRWYFPAFNLADSAITVGAV
MLALDMF
3D structure
PDB5dir Structural basis of lipoprotein signal peptidase II action and inhibition by the antibiotic globomycin.
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.23.36: signal peptidase II.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A N54 F59 N112 R116 D124 D143 I146 N53 F58 N111 R115 D123 D142 I145
BS02 peptide A F59 F73 R116 F58 F72 R115
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006465 signal peptide processing
GO:0006508 proteolysis
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5dir, PDBe:5dir, PDBj:5dir
PDBsum5dir
PubMed26912896
UniProtQ9HVM5|LSPA_PSEAE Lipoprotein signal peptidase (Gene Name=lspA)

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