Structure of PDB 5dig Chain A

Receptor sequence
>5digA (length=241) Species: 9606 (Homo sapiens) [Search protein sequence]
KNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADR
ELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKL
LFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSII
LLNSGVYTFLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLL
ILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRLH
3D structure
PDB5dig Predictive features of ligand-specific signaling through the estrogen receptor.
ChainA
Resolution2.24 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I358 V376 D538 E542 I56 V74 D229 E233
BS02 5CE A M343 E353 L387 M388 L391 F404 H524 M41 E51 L85 M86 L89 F102 H215
External links
PDB RCSB:5dig, PDBe:5dig, PDBj:5dig
PDBsum5dig
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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