Structure of PDB 5die Chain A

Receptor sequence
>5dieA (length=236) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILS
HIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB5die Predictive features of ligand-specific signaling through the estrogen receptor.
ChainA
Resolution2.24 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I358 L372 Q375 V376 D538 L539 E542 I54 L68 Q71 V72 D226 L227 E230
BS02 5CJ A M343 L346 A350 E353 L387 M388 L391 F404 G521 H524 M39 L42 A46 E49 L83 M84 L87 F100 G209 H212
External links
PDB RCSB:5die, PDBe:5die, PDBj:5die
PDBsum5die
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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