Structure of PDB 5def Chain A

Receptor sequence
>5defA (length=276) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFHTSVSRPGRGEPRFITVGYVDDTLFVRFDSDAASPREEPRAP
WIEQEGPEYWDRETQICKAKAQTDRESLRTLLRYYNQSEAGSHTLQNMYG
CDVGPDGRLLRGYHQDAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
REAEQLRAYLEGECVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEAT
LRCWALGFYPGEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
3D structure
PDB5def Increased Conformational Flexibility of HLA-B*27 Subtypes Associated With Ankylosing Spondylitis.
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y7 H9 T24 E45 R62 E63 Q65 I66 C67 T73 E76 S77 L81 Y84 Y99 Y123 T143 K146 W147 A150 E152 Q155 L156 Y159 E163 W167 Y171 Y7 H9 T24 E45 R62 E63 Q65 I66 C67 T73 E76 S77 L81 Y84 Y99 Y123 T143 K146 W147 A150 E152 Q155 L156 Y159 E163 W167 Y171
External links
PDB RCSB:5def, PDBe:5def, PDBj:5def
PDBsum5def
PubMed26748477
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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