Structure of PDB 5ddh Chain A

Receptor sequence
>5ddhA (length=274) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRW
3D structure
PDB5ddh Toxoplasma gondii peptide ligands open the gate of the HLA class I binding groove.
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 E63 R65 K66 H70 T73 D77 T80 Y99 Y116 T143 K146 W147 V152 Q155 L156 Y159 T163 W167 Y171 Y7 E63 R65 K66 H70 T73 D77 T80 Y99 Y116 T143 K146 W147 V152 Q155 L156 Y159 T163 W167 Y171
External links
PDB RCSB:5ddh, PDBe:5ddh, PDBj:5ddh
PDBsum5ddh
PubMed26824387
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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